Chlorcyclizine is a first-generation antihistamine of the phenylpiperazine class marketed in the United States and certain other countries. It is used primarily to treat allergy symptoms such as rhinitis, urticaria, and pruritus, and may also be used as an antiemetic. In addition to its antihistamine effects, chlorcyclizine also has some anticholinergic, antiserotonergic, and local anesthetic properties. It also has been studied as a potential treatment for hepatitis C.
氯环嗪
lǜ huán qín
更新时间:2024-04-29 20:47:15
- 常用名氯环嗪英文名1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine
- CAS号82-93-9分子量300.82600
- 密度N/A沸点137-145ºC at 0.1-0.15 MM HG
- 分子式C18H21ClN2熔点N/A
- MSDS闪点N/A
- 符号
GHS07
GHS09
信号词Warning
氯环嗪 名称
- 中文名氯环嗪
- 英文名1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine
- 中文别名氯苯甲嗪 |
- 英文别名Trihistan |Chlorcycline |Chlorocycline |Alergicide |Histantine |Diparalene |1-(4-chloro-benzhydryl)-4-methyl-piperazine |Histachlorazene |chlorcyclizine |Perazyl |1-[(4-chlorophenyl)(phenyl)methyl]-4-methylpiperazine |Chlorocyclizine |
氯环嗪 物理化学性质
- 沸点137-145ºC at 0.1-0.15 MM HG
- 分子式C18H21ClN2
- 分子量300.82600
- 精确质量300.13900
- PSA6.48000
- LogP3.55260
- 储存条件库房低温通风干燥
- 计算化学
1.疏水参数计算参考值(XlogP):无
2.氢键供体数量:0
3.氢键受体数量:2
4.可旋转化学键数量:3
5.互变异构体数量:无
6.拓扑分子极性表面积:6.5
7.重原子数量:21
8.表面电荷:0
9.复杂度:300
10.同位素原子数量:0
11.确定原子立构中心数量:0
12.不确定原子立构中心数量:1
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:1
氯环嗪 毒性和生态
氯环嗪 安全
- 符号GHS07, GHS09
- 信号词Warning
- 危害声明H302-H400
- 警示性声明P301 + P312 + P330
- 危险品运输编码UN 3077 9 / PGIII
- 海关编码2933599090
氯环嗪 合成路线
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氯环嗪 上游产品
氯环嗪上游产品 0
氯环嗪 海关
- 海关编码2933599090
- 中文概述2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
- Summary2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
氯环嗪 用途