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羟基积雪草苷
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更新时间：2024-05-08 21:47:06
- 常用名羟基积雪草苷英文名madecassoside
- CAS号34540-22-2分子量975.121
- 密度1.5±0.1 g/cm3沸点1043.6±65.0 °C at 760 mmHg
- 分子式C48H78O20熔点N/A
- MSDS闪点295.8±27.8 °C
- 符号信号词
羟基积雪草苷 名称
- 中文名羟基积雪草苷
- 英文名madecassoside
- 中文别名羟基积雪草甙 |
- 英文别名Asiaticoside A |MADESOIDE |RederMic |6-Deoxy-α-L-mannopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)-1-O-[(2α,3β,6β,14β)-2,3,6,23-tetrahydroxy-28-oxours-12-en-28-yl]-β-D-glucopyranose |β-D-Glucopyranose, O-6-deoxy-α-L-mannopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-1-O-[(2α,3β,6β,14β)-2,3,6,23-tetrahydroxy-28-oxours-12-en-28-yl]- |MADESOSIDE |Madecassoside |
羟基积雪草苷 生物活性
- 描述Madecassoside是一个从崩大碗中分离出来的五环三萜，有抗炎症。抗氧化和抗衰老的作用。
- 相关类别信号通路 >> 其他 >> 其他 天然产物 >> 萜类化合物和糖苷 研究领域 >> 其他
- 参考文献[1]. Zexin Li et al. Madecassoside suppresses proliferation and invasiveness of HGF-induced human hepatocellular carcinoma cells via PKC-cMET-ERK1/2-COX-2-PGE2 pathway. Int Immunopharmacol. 2016 Apr;33:24-32. [2]. Xia Y et al. Madecassoside ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting the generation of hepatocyte growth factor via PPAR-γ in colon. Br J Pharmacol. 2016 Apr;173(7):1219-35 [3]. Su Z et al. Protective effects of madecassoside against Doxorubicin induced nephrotoxicity in vivo and in vitro. Sci Rep. 2015 Dec 14
羟基积雪草苷 物理化学性质
- 密度1.5±0.1 g/cm3
- 沸点1043.6±65.0 °C at 760 mmHg
- 分子式C48H78O20
- 分子量975.121
- 闪点295.8±27.8 °C
- 精确质量974.508667
- PSA335.44000
- LogP1.88
- 外观性状白色粉末
- 蒸汽压0.0±0.6 mmHg at 25°C
- 折射率1.637
- 储存条件2-8°C
- 水溶解性H2O: soluble1mg/mL, clear, colorless
羟基积雪草苷 安全
- 安全声明 (欧洲)24/25
- 危险品运输编码NONH for all modes of transport
- WGK德国3
- RTECS号YU9625000
羟基积雪草苷 合成路线
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