0
Lumiracoxib, also known as CGS 35189 and COX 189, is a COX-2 selective inhibitor non-steroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige. Since its original approval, lumiracoxib has been withdrawn from the market in several countries, mostly due to its potential for causing liver failure (sometimes requiring liver transplantation). It has never been approved for use in the United States.
罗美昔布
luó měi xī bù
更新时间：2024-04-13 12:18:38
- 常用名罗美昔布英文名lumiracoxib
- CAS号220991-20-8分子量293.721
- 密度1.4±0.1 g/cm3沸点395.7±42.0 °C at 760 mmHg
- 分子式C15H13ClFNO2熔点139-141ºC
- MSDS闪点193.1±27.9 °C
- 符号信号词
罗美昔布 名称
- 中文名罗美昔布
- 英文名lumiracoxib
- 中文别名2-[(2-氯-6-氟苯基)氨基」-5-甲基苯乙酸 |鲁米昔布 |
- 英文别名2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-benzeneacetic acid |Prexige (Novartis) |2-(2-((2-chloro-6-fluorophenyl)amino)-5-methylphenyl)acetic acid |{2-[(2-Chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid |Prexige |COX189 |5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid |Joicela |Benzeneacetic acid, 2-[(2-chloro-6-fluorophenyl)amino]-5-methyl- |(2-((2-chloro-6-fluorophenyl)-amino)-5-methylphenyl)-acetic acid |Lumiracoxib |[14C]-Lumiracoxib |2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid |Lumiracoxib [USAN:INN] |
罗美昔布 物理化学性质
- 密度1.4±0.1 g/cm3
- 沸点395.7±42.0 °C at 760 mmHg
- 熔点139-141ºC
- 分子式C15H13ClFNO2
- 分子量293.721
- 闪点193.1±27.9 °C
- 精确质量293.061890
- PSA49.33000
- LogP3.90
- 外观性状淡黄色固体
- 蒸汽压0.0±1.0 mmHg at 25°C
- 折射率1.628
- 储存条件-20°C Freezer
罗美昔布 合成路线
共页
罗美昔布 上游产品
罗美昔布上游产品 0
罗美昔布 用途
浙公网安备
33020502000290号
