搜索

蒙莫西地那非

mēng mò xī dì nà fēi

名称

中文名

蒙莫西地那非
英文名

5-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
中文别名

蒙莫昔多芬 |好猫西地那非 |
英文别名

5-[2-ETHOXY-5-[(4-ETHYL-(PIPERAZIN-1-YL))SULFONYL]PHENYL]-1,6-DIHYDRO-1-METHYL-3-PROPYL-7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE |5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one |PYR397 |5-[2-ethoxy-5-(4-ethylpiperazine-1-yl-sulphonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one |7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl- |Homo Sildenafil |5-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one |UNII-0Z3JH0S0QK |

生物活性

描述

Homo Sildenafil 是 Sildenafil 的类似物，充当磷酸二酯酶 (phosphodiesterase) 抑制剂。
相关类别

研究领域 >> 内分泌信号通路 >> 代谢酶/蛋白酶 >> 磷酸二酯酶(PDE)
参考文献

[1]. Jackie D Corbin, et al. Vardenafil: Structural Basis for Higher Potency Over Sildenafil in Inhibiting cGMP-specific phosphodiesterase-5 (PDE5). Neurochem Int. 2004 Nov;45(6):859-63.

物理化学性质

合成路线

共页

热门搜索

搜索

化浪网