盐酸美托咪啶

yán suān měi tuō mī dìng

更新时间：2024-03-20 12:26:06

前往商城一键下单

盐酸美托咪啶名称

中文名

盐酸美托咪啶
英文名

medetomidine hydrochloride
中文别名

(R)-4-[1-(2,3-二甲基苯基)乙基]-1H-咪唑盐酸盐 |5-[1-(2,3-二甲基苯基)乙基]-1H-咪唑盐酸盐 |环丙氨嗪 |盐酸美托咪定 |
英文别名

4-[(a-Methyl)-2,3-dimethylbenzyl]imidazole Monohydrochloride |4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride (1:1) |1H-Imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1) |(±)-4-(a,2,3-Trimethylbenzyl)imidazole Monohydrochloride |1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1) |medetomidine HCl |UNII:BH210P244U |4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Monohydrochloride |Medetomidine (hydrochloride) |

盐酸美托咪啶生物活性

描述

Medetomidine(Domtor)盐酸盐是α2肾上腺素受体激动剂，对α2和α1肾上腺素受体的Ki分别为1.08 nM和1750 nM。
相关类别

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体研究领域 >> 神经疾病
参考文献

[1]. Davies, M.F., et al., Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala. Neuropsychopharmacology, 2004. 29(2): p. 229-39. [2]. Ozdogan, U.K., et al., The involvement of alpha 2A-adrenoceptors in morphine analgesia, tolerance and withdrawal in mice. Eur J Pharmacol, 2004. 497(2): p. 161-71. [3]. Menon, D.V., et al., Central sympatholysis as a novel countermeasure for cocaine-induced sympathetic activation and vasoconstriction in humans. J Am Coll Cardiol, 2007. 50(7): p. 626-33.

盐酸美托咪啶物理化学性质