概述名称生物活性物理化学性质毒性和生态安全合成路线上游产品下游产品海关

地索奈德

dì suǒ nài dé

更新时间：2024-04-03 18:54:37

我要供货

我要求购

前往商城一键下单

前往化浪商城点击直购

常用名

地索奈德

英文名

desonide
CAS号

638-94-8

分子量

416.507
密度

1.3±0.1 g/cm3

沸点

580.1±50.0 °C at 760 mmHg
分子式

C₂₄H₃₂O₆

熔点

274 - 275ºC
MSDS

闪点

196.9±23.6 °C
符号

信号词

地索奈德名称

中文名

地索奈德
英文名

desonide
中文别名
英文别名

Prednacinolone |(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one |16a,17a-Isopropylidenedioxyprednisolone |2H-naphth[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-, (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)- |Desowen |2H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-5-hydroxy-6b-(2-hydroxyacetyl)-4a,6a,8,8-tetramethyl-, (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)- |Locapred |Desonide |(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacétyl)-4a,6a,8,8-tétraméthyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodécahydro-2H-naphto[2',1':4,5]indéno[1,2-d][1,3]dioxol-2-one |Sterax |11b,16a,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione Cyclic 16,17-Acetal with Acetone |16a-Hydroxy-D1-hydrocortisone-16a,17a-acetonide |16a-Hydroxyprednisolone-16a,17-acetonide |Steroderm |16a-Hydroxyprednisolone Acetonide |TRIDESILON |desonidum [INN_la] |MFCD00866151 |11β,16α,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone |(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-Hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-on |(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one |11b,21-Dihydroxy-16a,17-isopropylidenedioxy-1,4-pregnadiene-3,20-dione |Topifug |d-2083 |EINECS 211-351-6 |11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione |Budesonide Impurity 6 |

地索奈德生物活性

描述

Desonide是非氟化皮质类固醇抗炎剂，能作用于糖皮质激素受体。
相关类别

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 糖皮质激素受体研究领域 >> 炎症/免疫
参考文献

[1]. Kahanek, N., C. Gelbard, and A. Hebert, Desonide: a review of formulations, efficacy and safety. Expert Opin Investig Drugs, 2008. 17(7): p. 1097-104. [2]. Castanedo-Cazares, J.P., et al., Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study. Clin Cosmet Investig Dermatol, 2013. 6: p. 29-36. [3]. Parish, D. and N. Scheinfeld, Desonide foam: a review. Drugs Today (Barc), 2008. 44(1): p. 55-62.

地索奈德物理化学性质