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5a-Pregnane-3,20-dione 是一种内源性的孕酮代谢物。
二氢黄体酮
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更新时间：2024-04-22 00:29:27
- 常用名二氢黄体酮英文名5α-pregnane-3,20-dione
- CAS号566-65-4分子量316.478
- 密度1.0±0.1 g/cm3沸点429.2±38.0 °C at 760 mmHg
- 分子式C21H32O2熔点N/A
- MSDS闪点160.3±23.8 °C
- 符号信号词
二氢黄体酮 名称
- 中文名氢化黄体酮
- 英文名5α-pregnane-3,20-dione
- 中文别名5Α-孕甾-3,20-二酮 |二氢黄体酮 |5-alpha-孕甾-3,20-二酮 |二氢黄体酮 |
- 英文别名5a-Dihydroprogesterone |4-07-00-02199 (Beilstein Handbook Reference) |Pregnane-3,20-dione, (5-α)- (9CI) |5alpha-Pregnan-3,20-dione |MFCD00067132 |Allopregnane-3,20-dione |(5S,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one |UNII:98G4S1OH0Z |5α-pregnane-3,20-dione |(5α)-Pregnane-3,20-dione |Pregnane-3,20-dione |5α-dihydroprogesterone |EINECS 209-297-3 |4-07-00-02199 |Allopregnan-3,20-dione |3,20-Allopregnanedione |5alpha-pregnane-3,20-dione |3,20-Dioxo-5a-pregnane |5a-Pregnan-3,20-dione |Pregnane-3,20-dione, (5α)- |Pregnane-3,20-dione, (5α)- (9CI) |3,20-Dioxo-5alpha-pregnane |5-α-pregnane-3,20-dione |allopregnandione |5alpha-Dihydroprogesterone |5a-Pregnane-3,20-dione |5α-Pregnane-3,20-dione (8CI) |(5Alpha)-Pregnane-3,20-dione |
二氢黄体酮 生物活性
- 描述5a-Pregnane-3,20-dione 是一种内源性的孕酮代谢物。
- 相关类别研究领域 >> 内分泌 天然产物 >> 黄酮类化合物
- 靶点Human Endogenous Metabolite
- 体外研究5a-Pregnane-3,20-dione减少MCF-7乳腺癌细胞中细胞 - 底物附着，粘附斑块，纽蛋白表达和聚合F-肌动蛋白[1]。
- 参考文献[1]. Wiebe JP, et al. The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells. Endocrine. 2001 Oct;16(1):7-14.
二氢黄体酮 物理化学性质
- 密度1.0±0.1 g/cm3
- 沸点429.2±38.0 °C at 760 mmHg
- 分子式C21H32O2
- 分子量316.478
- 闪点160.3±23.8 °C
- 精确质量316.240234
- PSA34.14000
- LogP4.31
- 外观性状白色固体
- 蒸汽压0.0±1.0 mmHg at 25°C
- 折射率1.516
二氢黄体酮 毒性和生态
二氢黄体酮 安全
- WGK德国3
- RTECS号TU4157150
二氢黄体酮 合成路线
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二氢黄体酮 用途
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